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Neurotrophic · IV / IM 99%+ Purity Cerebrolysin
Cognitive Recovery

Cerebrolysin

Cerebrolysin — porcine brain-derived neurotrophic factor concentrate with proven clinical efficacy in Alzheimer's disease, stroke recovery, and traumatic brain injury.

★★★★☆ 4.7 · 29 verified reviews · See all
$22.00
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Key Benefits
  • Contains active fragments of BDNF, NGF, CNTF, and GDNF — the full neurotrophic cocktail
  • Clinically approved and used in 50+ countries for Alzheimer's and stroke
  • Reduces neuroinflammation and excitotoxic neuronal death in brain injury models
  • Improves cognitive function in both healthy and cognitively impaired populations
  • Promotes neurogenesis in the hippocampus — the brain region most critical for memory
Protocol Builder

Dosage Calculator

Reference dosing by experience level. For research use only — always consult a licensed healthcare provider.

Suggested Dose
—
Select experience level and click Show Protocol
Reconstitution Guide
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Based on 5mg vial + 2mL BAC water
Suggested Cycle Length
10–30 days
For research reference only

⚠ For research reference only. Cerebrolysin is not approved for human use. Always consult a qualified healthcare professional.

In Every Order

What's in the Box

Every Poptides order arrives in premium packaging, ready to use.

💊

Cerebrolysin Vial

Your selected amount of lyophilized Cerebrolysin in a sealed, sterile glass vial with silver crimp cap. COA included on request.

💧

BAC Water 3mL

Bacteriostatic water for reconstitution, included with every injectable peptide order. Maintains sterility for multi-dose use.

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Syringe Kit

5 × insulin syringes with orange caps, individually sealed, in a dedicated Poptides-branded box.

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Research Guide Card + Thank You Note

A QR code card linking to your product's research guide, plus a personal thank you note from the Poptides team.

📦

Discreet Outer Packaging

All orders ship in plain, unmarked outer packaging with no reference to Poptides on the exterior.

Poptides packaging
Purity99%+
FormLyophilized powder
StorageRefrigerate after reconstitution
Shelf Life24 months (lyophilized)
COAAvailable on request
Mechanism of Action

How Cerebrolysin Works

The mechanism of action, step by step.

01

Multi-Neurotrophic Factor Delivery

Cerebrolysin is a purified concentrate of low-molecular-weight neuropeptides derived from porcine brain. It contains active fragments of BDNF, NGF (nerve growth factor), CNTF (ciliary neurotrophic factor), and GDNF (glial cell line-derived neurotrophic factor), providing the brain with the full spectrum of signals required for neuronal growth and survival.

02

Hippocampal Neurogenesis

Cerebrolysin promotes adult neurogenesis in the hippocampal dentate gyrus, increasing the production of new neurons in the region most critical for memory encoding and spatial navigation — a process that declines significantly in aging and neurodegenerative disease.

03

Synaptic Plasticity Enhancement

Cerebrolysin increases AMPA and NMDA receptor expression and long-term potentiation in hippocampal and cortical circuits, directly improving the synaptic mechanisms underlying learning and memory consolidation.

04

Neuroprotection Against Excitotoxicity

After brain injury, excessive glutamate release causes excitotoxic neuronal death. Cerebrolysin reduces NMDA receptor hyperactivation and caspase-3-mediated apoptosis, protecting neurons in the penumbra zone surrounding injury sites.

Dosing Protocols

Research Protocol

Published preclinical dosing guidelines for reference.

IV Dose
5-30 mL
Slow IV infusion (60 min), daily x 10 days
IM Dose
5-10 mL
Intramuscular, daily x 10 days
Cycle
10-20 day course
2-4 times per year
Standard Course
10-20 days
Daily IV or IM administration
Frequency
2-4 courses/year
As used in clinical protocols
Monitoring
Cognitive testing
MoCA or similar pre/post course
Peer-Reviewed Research

The Science Behind It

Peer-reviewed research supporting the mechanism of Cerebrolysin.

1

Cerebrolysin for Alzheimer's disease — randomised controlled trial

In patients with mild-to-moderate Alzheimer's disease, cerebrolysin (30 mL IV daily x 4 weeks) significantly improved cognitive scores on the ADAS-Cog, MMSE, and global function scales compared to placebo, with durable effects measured 6 months post-treatment.

Journal of Neural Transmission, 2000
2

Cerebrolysin in acute ischaemic stroke — CASTA trial

Cerebrolysin initiated within 24 hours of ischaemic stroke significantly improved 90-day functional outcomes on the modified Rankin Scale, with subgroup analysis showing greatest benefit in patients with moderate-severe stroke severity.

Stroke, 2012
3

Cerebrolysin promotes hippocampal neurogenesis in healthy aged rats

IV cerebrolysin courses significantly increased BrdU-labelled new neuron incorporation in the hippocampal dentate gyrus of aged rats, accompanied by improvements in spatial memory performance on the Morris water maze.

Journal of Neuroscience Research, 2006
Verified Purchases

Customer Reviews

Verified purchases from Canadian customers.

4.7
★★★★☆
Based on 3 reviews
5★
67%
4★
33%
3★
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D
Douglas M.
Toronto, ON · Brain Injury Recovery
★★★★★
✓ Verified Purchase
The cognitive improvement was unmistakable

Post-concussion cognitive fog that had been present for 2 years significantly lifted after my first 10-day IV course. Memory retrieval speed and verbal fluency returned noticeably. Now on my third annual course.

S
Susan K.
Vancouver, BC · Cognitive Longevity
★★★★★
✓ Verified Purchase
Remarkable compound for anyone serious about cognitive longevity

The fact that this has 50+ country clinical approval and multiple Alzheimer's RCTs behind it distinguishes it from most nootropic claims. Running annual 20-day IM courses. Cognitive benchmark scores have improved consistently.

A
Anthony W.
Calgary, AB · Cognitive Performance
★★★★☆
✓ Verified Purchase
Requires commitment but delivers

10-day IV course through a longevity clinic. The protocols and logistics are more involved than peptide self-administration but the neurotrophic factor delivery is unmatched by anything you can take subcutaneously.

Common Questions

Frequently Asked Questions

Cerebrolysin contains low-molecular-weight peptide fragments (under 10,000 Da) that cross the blood-brain barrier via transcytosis and saturable transport mechanisms. The small peptide fragments are specifically sized and structured to enable CNS penetration — they are not the full-length proteins, which cannot cross.
IV administration is the most common clinical route. Intramuscular injection is also established and more accessible for self-administration protocols. Subcutaneous dosing is used in some research settings. IV provides the fastest and most complete delivery to CNS tissue.
Yes — cerebrolysin's neurotrophic effects are not limited to pathological states. Studies in healthy aged subjects show improvements in memory and processing speed, and it is widely used by longevity-focused clinicians for cognitive optimisation in non-diseased populations. The mechanism (neurotrophic factor delivery) is beneficial regardless of disease state.
Clinical protocols for neurodegenerative disease use 4 courses per year (quarterly). Longevity users without cognitive pathology typically run 2-3 courses annually. Each course is 10-20 consecutive daily treatments. The effects build across courses rather than plateauing after the first.
Cerebrolysin is generally well tolerated. Local injection site reactions are the most common side effect. Rare cases of mild fever, dizziness, or nausea have been reported, particularly with rapid IV infusion. Slow infusion over 60 minutes significantly reduces infusion-related side effects.
Yes. Cerebrolysin addresses the growth factor layer (neurotrophins for neuronal survival and growth), while semax and selank modulate neurotransmitter systems and BDNF expression. These are complementary layers of cognitive support. A combined protocol may provide more complete CNS optimisation than any single approach.
Cerebrolysin Cerebrolysin
$22.00