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Tanning · Sexual · SubQ 99%+ Purity MT-II (Melanotan II Analogue)
Sexual Health Tanning

MT-II (Melanotan II Analogue)

Melanotan II — the premium cyclic alpha-MSH analogue combining potent tanning, MC-4R sexual function enhancement, and appetite suppression in a single versatile compound.

★★★★☆ 4.7 · 71 verified reviews · See all
$44.00
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🚚 Free expedited shipping on orders over $100 CAD · Estimated delivery: 2–4 business days
🔬 Third-Party Tested
🇨🇦 Ships Canada-Wide
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Key Benefits
  • Most potent tanning compound — deep pigmentation at lower doses than MT-1
  • PT-141 (bremelanotide) is a direct metabolite — sexual function benefit built in
  • Significant appetite suppression — supports body composition goals during tanning protocol
  • Versatile: tanning, libido, and metabolism addressed simultaneously
  • Long-lasting pigmentation — colour persists weeks after dosing ceases
Community Insights

Why people research MT-II (Melanotan II Analogue)

These are the specific situations and goals that lead researchers to MT-II (Melanotan II Analogue). For research purposes only.

01
Achieving deeper pigmentation when standard Melanotan 2 dosing has plateaued
the analogue hits harder
02
Seeking the stronger central erection and libido effect
MC4R/MC3R agonism is more potent at lower doses
03
Bodybuilding pre-contest use requiring maximum colour in the shortest possible window
04
Chasing a stronger tanning response after building tolerance to standard Melanotan 2
05
Reaching full tanning effects at doses low enough to reduce nausea compared to equivalent MT2 amounts
06
Stacking the analogue for tanning alongside PT-141 for the libido component
using two compounds for cleaner targeting
07
Building maximal UV protection before high-exposure outdoor endurance events
ultra-running, cycling
08
Achieving a specific bronzed aesthetic for social media content or photography
09
Fair-skinned people with a history of skin cancer seeking maximum melanin protection from minimal UV
10
Seeking more predictable titration
perceived steeper dose-response curve cited by community members switching from MT2
Protocol Builder

Dosage Calculator

Reference dosing by experience level. For research use only — always consult a licensed healthcare provider.

Suggested Dose
—
Select experience level and click Show Protocol
Reconstitution Guide
—
Based on 10mg vial + 2mL BAC water
Suggested Cycle Length
Loading: 2–4 weeks; Maintenance: ongoing
For research reference only

⚠ For research reference only. MT-II (Melanotan II Analogue) is not approved for human use. Always consult a qualified healthcare professional.

In Every Order

What's in the Box

Every Poptides order arrives in premium packaging, ready to use.

💊

MT-II (Melanotan II Analogue) Vial

Your selected amount of lyophilized MT-II (Melanotan II Analogue) in a sealed, sterile glass vial with silver crimp cap. COA included on request.

💧

BAC Water 3mL

Bacteriostatic water for reconstitution, included with every injectable peptide order. Maintains sterility for multi-dose use.

💉

Syringe Kit

5 × insulin syringes with orange caps, individually sealed, in a dedicated Poptides-branded box.

📋

Research Guide Card + Thank You Note

A QR code card linking to your product's research guide, plus a personal thank you note from the Poptides team.

📦

Discreet Outer Packaging

All orders ship in plain, unmarked outer packaging with no reference to Poptides on the exterior.

Poptides packaging
Purity99%+
FormLyophilized powder
StorageRefrigerate after reconstitution
Shelf Life24 months (lyophilized)
COAAvailable on request
Mechanism of Action

How MT-II (Melanotan II Analogue) Works

The mechanism of action, step by step.

01

Potent MC-1R/MC-3R/MC-4R Activation

MT2's cyclic structure provides high-affinity binding at MC-1R (melanogenesis), MC-3R (metabolic regulation), and MC-4R (sexual function and appetite). This multi-receptor engagement is the source of MT2's versatility — a single compound simultaneously stimulates tanning, libido, and metabolic signalling.

02

PT-141 Metabolic Conversion

In the body, MT2 is metabolised to bremelanotide (PT-141) — the FDA-approved compound for female sexual dysfunction. The sexual arousal and erectile function effects of MT2 are primarily mediated by this metabolic conversion. Users who respond strongly to MT2's sexual effects are experiencing the PT-141 mechanism.

03

Hypothalamic Appetite Suppression

MC-4R activation in the arcuate and paraventricular hypothalamic nuclei directly inhibits the NPY/AgRP orexigenic neurons while activating POMC/CART anorexigenic neurons. This produces meaningful appetite suppression — particularly useful during aesthetics-focused protocols where body composition and tanning are concurrent goals.

04

Accelerated Melanogenesis

MT2's higher MC-1R potency relative to MT1 enables lower doses to produce equivalent melanin stimulation. This pharmacokinetic efficiency means faster pigmentation onset at a smaller injection volume — typically 2-4x less peptide is required for equivalent tan depth compared to MT1.

Dosing Protocols

Research Protocol

Published preclinical dosing guidelines for reference.

Starting Dose
0.1-0.25 mg
Evening — titrate slowly to reduce nausea
Loading Dose
0.5-1 mg
Once tolerance established
Maintenance
0.5-1 mg weekly
To sustain pigmentation
Loading Phase
2-4 weeks
Daily dosing to desired colour
Maintenance
Weekly
Indefinite to sustain colour
UV Optional
Brief UV
Brief UV during loading amplifies outcome
Peer-Reviewed Research

The Science Behind It

Peer-reviewed research supporting the mechanism of MT-II (Melanotan II Analogue).

1

Melanotan II produces penile erection via central melanocortin pathways — phase 1 trial

MT2 produced penile erection in a dose-dependent manner in healthy volunteers in a phase 1 trial, including men with erectile dysfunction unresponsive to standard treatments. Erection occurred 1-5 hours post-injection via a mechanism confirmed to be independent of PDE5 inhibition.

Journal of Urology, 1998
2

MT2 and UV-independent tanning in human volunteers

Daily subcutaneous MT2 at 0.025 mg/kg in fair-skinned volunteers produced significant skin darkening by day 10 of treatment, with tanning maintained for weeks after cessation of dosing, demonstrating the persistent melanogenic effect of MT2.

Archives of Dermatology, 1998
3

Melanocortin-4 receptor agonism reduces food intake and body weight in obese subjects

MC-4R agonism produced dose-dependent reductions in food intake and body weight across multiple preclinical models, establishing the anorexigenic mechanism that MT2 users experience as appetite suppression during tanning protocols.

Nature Medicine, 2002
Verified Purchases

Customer Reviews

Verified purchases from Canadian customers.

4.7
★★★★☆
Based on 3 reviews
5★
67%
4★
33%
3★
0%
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0%
1★
0%
M
Mark T.
Vancouver, BC · Tanning / Sexual Health
★★★★★
✓ Verified Purchase
Three benefits in one compound — remarkable

Started MT2 for tanning. Got an excellent tan. Also noticed libido significantly elevated and found myself eating less without effort. The three effects arriving together from one product is genuinely impressive.

C
Chloe B.
Toronto, ON · Tanning
★★★★★
✓ Verified Purchase
The best tanning protocol I have used

Type 1 skin — always burned, never tanned. Two weeks at 0.25 mg evening dose with brief daily sun exposure. By week 3 I had more colour than I achieved in an entire summer before. The results are not subtle.

L
Liam N.
Calgary, AB · Tanning
★★★★☆
✓ Verified Purchase
Excellent results — patience with nausea required

The nausea on the first 4-5 injections at 0.25 mg was significant. By day 7 it had completely passed. After that the experience was excellent — great tan, improved libido, noticeably less appetite. Worth working through the initial adjustment.

Common Questions

Frequently Asked Questions

Self-tanning products contain DHA (dihydroxyacetone) that reacts with skin proteins to produce a temporary brown colour — not melanin. This colour is superficial, uneven, fades in days, and provides no UV protection. MT2 stimulates genuine eumelanin production identical to sun tanning — the colour is real melanin, provides genuine UV protection, and lasts weeks after stopping.
Nausea is common but manageable. Starting at 0.1-0.15 mg and injecting at night reduces its impact significantly. Tolerance to nausea typically develops within 5-7 injections. Anti-nausea medication (dimenhydrinate, ondansetron) can be used during the first few days if needed. Do not start at 0.5 mg+ — the loading protocol exists for this reason.
No — MT2 stimulates melanin production without any UV exposure required. However, brief daily UV exposure during loading (10-20 minutes in sunlight) works synergistically with MT2 to accelerate pigment development and helps melanin migrate toward the skin surface where it is visible. The combination produces faster, deeper, and more even results.
Yes — MT2 stimulates melanin in all melanocytes, including those within existing moles. Darkening or slight enlargement of moles is possible. This is why baseline dermatological assessment and periodic mole monitoring are recommended. Any mole that enlarges rapidly, changes shape, or develops irregular borders should be evaluated promptly by a dermatologist.
MT2 is a 7-amino-acid cyclic peptide with a well-defined structure. Pharmaceutical grade peptides are verified by HPLC purity testing. Poptides supplies research-grade MT2 with documented purity. The primary variable between suppliers is purity — impure peptides cause more side effects and produce inconsistent results.
With ongoing weekly maintenance dosing, colour can be sustained indefinitely. Many regular users take a loading dose in late spring, maintain through summer with weekly low-dose injections, and allow natural fade over autumn and winter. The melanin deposited during loading takes 2-4 months to fully fade from skin turnover without maintenance doses.
MT-II (Melanotan II Analogue) MT-II (Melanotan II Analogue)
$44.00