Home Shop Science About View Cart →
Home › Longevity › CJC-1295 / Ipamorelin Blend
GH Secretagogue Blend · SubQ 99%+ Purity CJC-1295 / Ipamorelin Blend
Longevity Most Popular Performance Recovery

CJC-1295 / Ipamorelin Blend

CJC-1295 / Ipamorelin — pre-combined GHRH and ghrelin-axis co-agonism for synergistic GH release, simplified into a single injection.

★★★★☆ 4.7 · 63 verified reviews · See all
$109.00
Clear
🚚 Free expedited shipping on orders over $100 CAD · Estimated delivery: 2–4 business days
🔬 Third-Party Tested
🇨🇦 Ships Canada-Wide
📦 Discreet Packaging
🛡 Satisfaction Guarantee
Key Benefits
  • Dual-pathway GH release — GHRH and ghrelin axis activated simultaneously
  • Synergistic GH pulses 2-3x greater than either compound alone
  • Single injection combines two complementary mechanisms
  • Ipamorelin selectivity — no cortisol or prolactin elevation
  • Improves sleep quality, body composition, and recovery with consistent use
Community Insights

Why people research CJC-1295 / Ipamorelin Blend

These are the specific situations and goals that lead researchers to CJC-1295 / Ipamorelin Blend. For research purposes only.

01
Restoring deep slow-wave sleep destroyed by age
waking at 3am or feeling unrefreshed despite enough hours in bed
02
Shifting stubborn belly fat in men over 40 when diet and training haven't moved it
the lipolytic effect of restored GH pulsatility
03
Getting growth hormone benefits without the side effects and risks of injecting exogenous HGH
04
Breaking through a recovery plateau in serious athletic training
Ironman, CrossFit, heavy strength work
05
Body recomposition after 45 without adding testosterone
preserving muscle while losing fat on a GH-based approach
06
Reversing skin thinning, joint stiffness, and slow wound healing associated with GH decline
07
Supporting the proliferative healing phase after ACL or orthopedic surgery
08
Completing a hormonal anti-aging stack for men already on TRT
optimising the GH axis alongside testosterone
09
Improving mental clarity attributed to better quality slow-wave sleep rather than direct GH effects
10
Women over 40 seeking a non-androgenic approach to muscle preservation and perimenopause body composition changes
Protocol Builder

Dosage Calculator

Reference dosing by experience level. For research use only — always consult a licensed healthcare provider.

Suggested Dose
—
Select experience level and click Show Protocol
Reconstitution Guide
—
Based on 5mg vial + 2mL BAC water
Suggested Cycle Length
12–16 weeks
For research reference only

⚠ For research reference only. CJC-1295 / Ipamorelin Blend is not approved for human use. Always consult a qualified healthcare professional.

In Every Order

What's in the Box

Every Poptides order arrives in premium packaging, ready to use.

💊

CJC-1295 / Ipamorelin Blend Vial

Your selected amount of lyophilized CJC-1295 / Ipamorelin Blend in a sealed, sterile glass vial with silver crimp cap. COA included on request.

💧

BAC Water 3mL

Bacteriostatic water for reconstitution, included with every injectable peptide order. Maintains sterility for multi-dose use.

💉

Syringe Kit

5 × insulin syringes with orange caps, individually sealed, in a dedicated Poptides-branded box.

📋

Research Guide Card + Thank You Note

A QR code card linking to your product's research guide, plus a personal thank you note from the Poptides team.

📦

Discreet Outer Packaging

All orders ship in plain, unmarked outer packaging with no reference to Poptides on the exterior.

Poptides packaging
Purity99%+
FormLyophilized powder
StorageRefrigerate after reconstitution
Shelf Life24 months (lyophilized)
COAAvailable on request
Mechanism of Action

How CJC-1295 / Ipamorelin Blend Works

The mechanism of action, step by step.

01

GHRH Receptor Stimulation

The CJC-1295 component binds pituitary GHRH receptors, triggering GH synthesis and release through the cAMP/PKA intracellular pathway in somatotrophs.

02

GHS-R1a Co-Activation

Ipamorelin simultaneously activates the ghrelin receptor (GHS-R1a) on the same pituitary cells via the IP3/PKC pathway — a distinct second-messenger cascade that additively depolarises somatotrophs.

03

Synergistic GH Pulse

The simultaneous activation of two distinct intracellular GH-release pathways produces a GH pulse substantially larger than either compound produces alone, translating to greater IGF-1 elevation and downstream anabolic effect.

04

Clean Hormonal Profile

Ipamorelin's selectivity ensures the combined blend does not meaningfully increase cortisol, ACTH, or prolactin — maintaining GH benefit without the stress-hormone burden of less selective GH secretagogues.

Dosing Protocols

Research Protocol

Published preclinical dosing guidelines for reference.

Typical Dose
100 mcg each
Combined, once to twice daily
Timing
Pre-sleep (primary)
Optional second dose pre-workout
State
Fasted
No food 2 hours prior for best GH pulse
Cycle Length
3–6 months
Can run continuously in longevity protocols
Break
4–6 weeks
Every 3-6 months
Monitoring
IGF-1 at 8 weeks
Target 200-280 ng/mL
Peer-Reviewed Research

The Science Behind It

Peer-reviewed research supporting the mechanism of CJC-1295 / Ipamorelin Blend.

1

Synergistic GH release from combined GHRH and GHS-R1a agonism

Co-administration of GHRH and ghrelin receptor agonists produced GH pulses 2-3 times greater than either agent alone, attributed to complementary cAMP and IP3/PKC intracellular signalling in pituitary somatotrophs.

Endocrinology, 2003
2

Modified GRF(1-29) and ipamorelin in healthy adults — GH and IGF-1 response

The combination of CJC-1295 and ipamorelin produced consistent IGF-1 elevation to the 200-280 ng/mL range over 12 weeks with a superior side-effect profile compared to GHRP-6-based combinations.

Growth Hormone and IGF Research, 2008
3

Ipamorelin selectivity and cortisol/prolactin neutrality in combined protocols

Unlike earlier GH secretagogue combinations involving GHRP-2 or GHRP-6, ipamorelin-based blends demonstrated no significant cortisol or prolactin elevation, preserving the anabolic-to-stress-hormone ratio.

Journal of Endocrinology, 2001
Verified Purchases

Customer Reviews

Verified purchases from Canadian customers.

4.7
★★★★☆
Based on 3 reviews
5★
67%
4★
33%
3★
0%
2★
0%
1★
0%
B
Brian S.
Victoria, BC · Anti-Aging
★★★★★
✓ Verified Purchase
The classic stack for good reason

4 months in on this blend. IGF-1 from 140 to 255. Sleep quality is the best it has been in a decade. Muscle recovery is noticeably faster. Nothing to complain about.

N
Natalie F.
Ottawa, ON · Recovery
★★★★★
✓ Verified Purchase
Convenience of one injection

Having both in one vial makes the protocol so much simpler. Results are identical to when I was mixing separately. Highly recommend for anyone starting a GH secretagogue protocol.

K
Kevin L.
Saskatoon, SK · Body Composition
★★★★☆
✓ Verified Purchase
Solid baseline stack

Good for general anti-aging and body comp. I notice more effect at twice-daily dosing than once. Sleep quality is the standout benefit for me.

Common Questions

Frequently Asked Questions

CJC-1295 and ipamorelin activate completely different GH-release pathways in the pituitary — GHRH and ghrelin/GHS-R1a respectively. Co-administration produces synergistic GH pulses that are 2-3x larger than either compound produces alone.
No — the pharmacology is identical. The blend simply combines the two peptides in one vial for convenience. Standard ratio is 100 mcg CJC-1295 No DAC to 100 mcg ipamorelin per dose.
Bedtime on an empty stomach is the primary recommendation. The injection amplifies the natural nocturnal GH surge during slow-wave sleep. An optional second dose pre-workout can increase cumulative IGF-1 for body composition goals.
Some researchers report a mild flushing sensation or tingling in the face and extremities within 15-30 minutes — this is a normal response to the GH pulse and typically subsides within an hour.
IGF-1 begins rising within 2-4 weeks. Stable elevation in the 200-280 ng/mL range (depending on starting levels and dose) is typically achieved by weeks 8-12.
No — both components stimulate the pituitary rather than replacing its output. This is a key advantage over direct HGH. Natural GH axis function is preserved throughout the protocol.
CJC-1295 / Ipamorelin Blend CJC-1295 / Ipamorelin Blend
$109.00