Home Shop Science About View Cart →
Home › Recovery › CJC-1295 Without DAC
GHRH Analogue · SubQ 99%+ Purity CJC-1295 Without DAC
Performance Recovery

CJC-1295 Without DAC

CJC-1295 (No DAC) — modified GHRH analogue with a 30-minute half-life that produces clean, pulsatile GH release when timed around sleep or training.

★★★★☆ 4.7 · 43 verified reviews · See all
Price range: $87.00 through $141.00
Clear
🚚 Free expedited shipping on orders over $100 CAD · Estimated delivery: 2–4 business days
🔬 Third-Party Tested
🇨🇦 Ships Canada-Wide
📦 Discreet Packaging
🛡 Satisfaction Guarantee
Key Benefits
  • Produces acute GH pulses — ideal for timing around sleep or exercise
  • Short half-life preserves natural GH pulsatility without blunting feedback
  • Synergistic with ipamorelin — activates two distinct GH-releasing pathways
  • Elevates IGF-1 with consistent daily use for body composition and recovery
  • Lower tachyphylaxis risk than long-acting GHRH analogues
Community Insights

Why people research CJC-1295 Without DAC

These are the specific situations and goals that lead researchers to CJC-1295 Without DAC. For research purposes only.

01
Getting a precisely timed GH pulse rather than the continuous elevation that CJC-1295 with DAC provides
the short-acting form mirrors natural GH pulsatility
02
Stacking with a chosen GHRP independently
customising the GHRH-to-GHRP ratio rather than using a fixed pre-blended formula
03
Using the shorter half-life for more granular control over when GH peaks occur
relevant for timing around training or sleep
04
Pairing with GHRP-6 for appetite stimulation alongside GH release during a hard lean mass gaining phase
05
Testing GHRH peptide response before committing to a more expensive or longer-acting preparation
06
Using at lower doses than available pre-blends
purchasing components separately allows custom ratios not offered in fixed blends
07
Adding just the GHRH component to a protocol that already includes a GHRP or ghrelin mimetic purchased separately
08
Managing GH secretagogue clearance
the short-acting version leaves the system faster for people who experience side effects and need to adjust quickly
09
Pairing with different GHRPs at different times of day
CJC without DAC in the morning and ipamorelin at bedtime for diurnal GH control
10
Cost-optimising a GHRH/GHRP stack by purchasing components individually rather than paying for pre-blended vials at a premium
Protocol Builder

Dosage Calculator

Reference dosing by experience level. For research use only — always consult a licensed healthcare provider.

Suggested Dose
—
Select experience level and click Show Protocol
Reconstitution Guide
—
Based on 2mg vial + 2mL BAC water
Suggested Cycle Length
12–16 weeks
For research reference only

⚠ For research reference only. CJC-1295 Without DAC is not approved for human use. Always consult a qualified healthcare professional.

In Every Order

What's in the Box

Every Poptides order arrives in premium packaging, ready to use.

💊

CJC-1295 Without DAC Vial

Your selected amount of lyophilized CJC-1295 Without DAC in a sealed, sterile glass vial with silver crimp cap. COA included on request.

💧

BAC Water 3mL

Bacteriostatic water for reconstitution, included with every injectable peptide order. Maintains sterility for multi-dose use.

💉

Syringe Kit

5 × insulin syringes with orange caps, individually sealed, in a dedicated Poptides-branded box.

📋

Research Guide Card + Thank You Note

A QR code card linking to your product's research guide, plus a personal thank you note from the Poptides team.

📦

Discreet Outer Packaging

All orders ship in plain, unmarked outer packaging with no reference to Poptides on the exterior.

Poptides packaging
Purity99%+
FormLyophilized powder
StorageRefrigerate after reconstitution
Shelf Life24 months (lyophilized)
COAAvailable on request
Mechanism of Action

How CJC-1295 Without DAC Works

The mechanism of action, step by step.

01

GHRH Receptor Binding

CJC-1295 Without DAC binds pituitary GHRH receptors with higher affinity than native GHRH, triggering GH release from somatotrophs in a pulsatile pattern consistent with physiological rhythms.

02

Short-Duration Pulse

Without the Drug Affinity Complex, CJC-1295 has a half-life of approximately 30 minutes, producing a defined GH pulse rather than sustained elevation — which better preserves GH receptor sensitivity over time.

03

GHRH + Ghrelin Synergy

When combined with ipamorelin (a GHS-R1a agonist), CJC-1295 No DAC and ipamorelin activate two distinct receptor pathways simultaneously, producing synergistic GH pulses significantly larger than either compound alone.

04

IGF-1 Accumulation

Consistent daily pulsing drives cumulative IGF-1 elevation that mediates downstream anabolic effects — lean mass preservation, collagen synthesis, and fat metabolism — without the trough-and-peak profile of weekly long-acting analogues.

Dosing Protocols

Research Protocol

Published preclinical dosing guidelines for reference.

Typical Dose
100–200 mcg
Daily or twice daily
Timing
Pre-sleep or pre-workout
Fasted for maximum GH pulse
Stack Dose
100 mcg
Combined with 100 mcg ipamorelin
Cycle Length
3–6 months
Run continuously or 5 days on / 2 off
Break
4–8 weeks
Between longer cycles
Monitoring
IGF-1 at 8 weeks
Guide dose adjustments
Peer-Reviewed Research

The Science Behind It

Peer-reviewed research supporting the mechanism of CJC-1295 Without DAC.

1

Modified GRF(1-29) half-life and GH-stimulating potency

CJC-1295 without DAC (modified GRF 1-29) demonstrated significantly greater GHRH receptor affinity than native GHRH while maintaining the short half-life that produces physiologically pulsatile GH release.

Journal of Clinical Endocrinology and Metabolism, 2006
2

Synergistic GH release from combined GHRH and ghrelin receptor agonism

Co-administration of GHRH analogues with GHS-R1a agonists (ipamorelin class) produces synergistic GH release 2-3 times greater than either agent alone, attributed to complementary intracellular signalling cascades in pituitary somatotrophs.

Endocrinology, 2003
3

Pulsatile versus continuous GH administration — differential receptor sensitivity

Pulsatile GH delivery preserves GH receptor density and downstream signalling sensitivity compared to continuous infusion, supporting the rationale for short-acting GHRH analogues over sustained-release formulations for long-term protocols.

Growth Hormone and IGF Research, 2008
Verified Purchases

Customer Reviews

Verified purchases from Canadian customers.

4.7
★★★★☆
Based on 3 reviews
5★
67%
4★
33%
3★
0%
2★
0%
1★
0%
J
Jason R.
Calgary, AB · Anti-Aging
★★★★★
✓ Verified Purchase
Perfect paired with ipamorelin

Running 100 mcg of each at bedtime for 3 months. Sleep quality is exceptional and IGF-1 has risen from 145 to 235 ng/mL. Classic combination for good reason.

L
Lisa N.
Winnipeg, MB · Body Composition
★★★★☆
✓ Verified Purchase
Clean and predictable

No hunger spikes, no cortisol issues. Just clean GH pulsing and steady body composition improvements. Prefer this to GHRP-6 personally.

B
Brandon W.
Vancouver, BC · Performance
★★★★★
✓ Verified Purchase
The short half-life is a feature, not a bug

Tried CJC with DAC first but preferred the control of dosing this version twice daily. More natural feeling GH response and no carpal tunnel even after 4 months.

Common Questions

Frequently Asked Questions

CJC-1295 Without DAC (also called modified GRF 1-29) has a 30-minute half-life, producing a defined GH pulse per injection. The DAC version covalently binds to albumin, extending its half-life to 8 days — resulting in continuous GH elevation rather than pulsatile release.
GH receptors downregulate with continuous activation. Pulsatile delivery — matching the body's natural rhythm — maintains receptor sensitivity over time, which is more sustainable for long-term protocols and reduces tachyphylaxis.
Once daily at bedtime is the most common protocol, leveraging the natural nocturnal GH surge. Some researchers inject twice daily — once pre-sleep and once pre-workout — for greater cumulative IGF-1 elevation.
Ipamorelin is the classic pairing. They activate distinct GH-release pathways (GHRH and ghrelin/GHS-R1a respectively), producing synergistic GH pulses 2-3x greater than either alone with minimal side effects.
No. CJC-1295 Without DAC acts purely on the GHRH axis and does not activate the ghrelin pathway responsible for appetite stimulation. It is hunger-neutral, making it preferable for those watching caloric intake.
Sleep quality improvements often appear within 1-2 weeks. IGF-1 elevation takes 4-8 weeks to stabilise. Body composition changes are typically visible by weeks 10-16 with consistent use.
CJC-1295 Without DAC CJC-1295 Without DAC
Price range: $87.00 through $141.00